Record results clouded by climate change and conflict hampering progress – Press Releases

Record results clouded by climate change and conflict hampering progress – Press Releases

Record results clouded by climate change and conflict hampering progress

Progress in the fight against HIV, tuberculosis and malaria has exceeded pre-Covid-19 levels, but the growing crisis threatens achievement of the 2030 targets.

September 18, 2023

GENEVA – Report on results for 2023. [ télécharger en عربي | 中文 | Deutsch | English | Español | Français | Italiano | 日本語 | 한국어 | Português ] The Global Fund, released today (read the full report), shows marked improvement in program outcomes for HIV, tuberculosis and malaria after setbacks during the COVID-19 pandemic. However, numerous challenges such as climate change, conflict, growing inequality and growing threats to human rights are taking us further and further away from the goal of ending AIDS, tuberculosis and malaria by 2030.

“Collectively, the Global Fund’s partnerships have saved 59 million lives over the past 20 years,” said Peter Sands, Executive Director of the Global Fund. While we achieved record results in 2022, extraordinary measures will be required to achieve our 2030 targets.”

In 2022, thanks to the efforts, adaptations and innovations of governments, communities and our partners, the Global Fund partnership provided an unprecedented number of people living with HIV with antiretroviral treatment. We found and treated more people with tuberculosis than ever before, and distributed a record number of mosquito nets to prevent malaria.

Key results for 2022 in countries where the Global Fund invests:


  • 24.5 million people are receiving antiretroviral treatment for HIV.
  • 53.1 million HIV tests conducted (12.2 million in key and priority populations).
  • 15.3 million people are covered by HIV prevention services.
  • 710,000 mothers living with HIV are receiving treatment to stay alive and prevent passing HIV to their children.
  • 831,000 voluntary medical male circumcisions for HIV prevention.


  • 6.7 million people were treated for tuberculosis.
  • 118,000 people are receiving treatment for drug-resistant tuberculosis.
  • 331,000 tuberculosis and HIV patients are receiving antiretroviral treatment.
  • 2.2 million people living with HIV and receiving antiretroviral treatment are receiving preventive treatment for tuberculosis.
  • 1.5 million people became infected with tuberculosis through preventive treatment.


  • 220 million mosquito nets distributed to protect families from malaria.
  • 321 million suspected cases of malaria tested.
  • 37.1 million children receive chemoprophylaxis for seasonal malaria.
  • 14.6 million pregnant women receive preventive treatment for malaria.
  • 165 million cases of malaria cured.

Colliding crises slow progress

In many countries where the Global Fund invests, getting back on track to combat these three diseases has been made even more difficult by a combination of interconnected and conflicting crises beyond COVID-19. Examples include climate change, conflict and debt, as well as alarming violations of human rights and growing inequality within and between countries.

Climate change is already affecting the epidemiology of infectious diseases. For example, malaria is spreading to mountainous areas of Africa that were previously too cold for the Anopheles mosquitoes that carry the disease. Cyclones, floods and other climate-related disasters cause malaria outbreaks, as seen in Malawi and Pakistan. Food insecurity and water shortages are forcing entire communities to flee the country, leaving them more vulnerable to diseases, including tuberculosis. The Global Fund has stepped up its efforts to mitigate the impact of extreme weather events on malaria programs and ensure continuity of HIV and tuberculosis services.

The conflict is damaging health infrastructure and straining already overstretched health services. Sick people no longer have access to treatment, supply chains are disrupted, and prevention efforts are disrupted. In Sudan, Ukraine, Afghanistan, Myanmar and other countries, Global Fund partnerships face enormous challenges in ensuring the most vulnerable people have access to essential services.

Strengthening health systems to control and prevent pandemics

Sustainable and sustainable health systems are key to successfully combating these three diseases. They are also the basis for prevention, detection and response to existing and emerging health threats.

According to Peter Sands, “By investing in the core components that make health systems resilient and resilient, the Global Fund is helping countries fight today’s killer infectious diseases and prepare for tomorrow’s health threats. For example, we will continue our important work supporting local health workers and strengthening supply chains and laboratory networks. »

In total, the Global Fund has committed more than US$5 billion to help countries respond to COVID-19, of which approximately US$2.2 billion will be invested in strengthening health systems and pandemic preparedness.

Improving equitable access to innovative, game-changing tools

Equitable access to innovative tools is a key element that must be improved if we are to regain and maintain momentum in the fight against HIV, tuberculosis and malaria.

Peter Sands notes that “despite the challenges, we can still achieve the goal of ending AIDS, tuberculosis and malaria as public health threats. We know what to do, we have working tools and success stories that inspire us. We must improve access to game-changing innovations and optimize their adoption alongside existing tools to maximize the impact of every dollar. We must address the inequalities that exacerbate the vulnerabilities of young women, key populations and the poorest. »

Against HIVThe new dapivirine vaginal ring, the first effective female-controlled HIV prevention product, gives women and girls the opportunity to protect themselves from HIV infection. HIV infection in children remains an area of ​​unmet need worldwide. However, recent innovations in treatment may change this. The Global Fund partnership is investing in a pediatric dolutegravir regimen—a treatment that is more effective, less expensive, and better tolerated by children.

Against tuberculosisSeveral innovations have emerged: new diagnostic tools such as mobile X-ray machines and low-cost molecular diagnostics; new treatments such as the therapeutic combination BPaLM (bedaquiline, pretomanid, linezolid and moxifloxacin) for the treatment of drug-resistant tuberculosis; and 3HP, a new short-term preventive treatment for tuberculosis.

Against malariaA range of innovations in vector control, prevention, diagnosis and treatment will help us reverse alarming trends in infections and deaths. For example, insecticide-treated dual-action bed nets combining pyrethroids and chlorfenapyr, which will become widely available from 2024, are significantly more effective than standard bed nets containing only pyrethroids. Trials demonstrated a reduction in malaria incidence of approximately 50% in children aged six months to ten years.

To get disease control back on track, it will be important to optimize the comprehensive implementation of these innovations while accelerating efforts to address the gross inequalities that fuel infectious diseases. It is by empowering the hardest-hit communities that the Global Fund ensures that life-saving services reach the most vulnerable people, including those marginalized due to poverty, social exclusion, discrimination or criminalization. Our model of putting people and communities at the center of our actions helps build the bonds of trust without which we could not achieve our mission and ensure no one is left behind.

Hi, I’m laayouni2023