Health.  How oral hygiene affects your overall health
Sciences et technologies

Health. How oral hygiene affects your overall health

Periodontal diseases: gingivitis and periodontitis.

Periodontitis is an inflammatory reaction that affects the periodontium, that is, all the structures that provide fixation of the teeth (gums, ligaments, alveolar process). It is caused by gingivitis, a local inflammation of the gums that has no cure.

Periodontitis causes gradual gum resorption and, where applicable, tooth loss. It is also the leading cause of tooth loss.

This disease and its associated bacteria are also associated with many other diseases: cardiovascular disease, diabetes, cancer, etc.

Cardiovascular diseases

Infective endocarditis is a serious infection of the endocardium (the tissue lining the chambers of the heart) associated with a high mortality rate.

This is often the result of the presence of bacteria in the blood (bacteremia), the starting point of which is usually the mouth and teeth, emphasizes the Higher Health Authority.

Specifically, the infection occurs from plaque bacteria that enter the bloodstream, reach the heart and attach to its internal cavities.

Several studies have also pointed to a link between periodontal disease and atherosclerosis (the formation of atherosclerotic plaque in artery walls), which is the cause of most cardiovascular diseases.

According to a specialized online magazine Dental flosstwo different mechanisms may operate or even be combined.

On the one hand, periodontal bacteria are found in the blood circulation and increase existing atherosclerotic plaques.

On the other hand, “periodontal diseases cause an immunoinflammatory reaction, which leads to the production of proinflammatory mediators, prothrombotic factors, which are detected through the systemic circulation at the level of atherosclerotic plaques.”

Diabetes

The relationship between diabetes and periodontal disease has been widely documented. Thus, poorly controlled diabetes will triple the risk of developing periodontal disease. Indeed, chronic inflammation associated with diabetes contributes to the destruction of periodontal structures.

Conversely, “chronic inflammation caused by periodontitis increases insulin resistance and, in turn, impairs blood sugar control,” summarizes the Prevention Observatory of the Montreal Heart Institute (Canada).

IBD

Periodontitis and inflammatory bowel disease (IBD) are also thought to be related. Bacteria that enter the body through saliva contribute to intestinal inflammation by disrupting the intestinal microbiome (intestinal flora consisting of billions of microorganisms). As with diabetes, the reverse is also true.

Alzheimer’s disease

Periodontal disease may be associated with Alzheimer’s disease, again due to bacteria from the gums entering the bloodstream.

P. gingivalis, the bacterium most commonly found in periodontitis, was found in the brains of patients with Alzheimer’s disease, according to a study.

It will have a negative effect on Tau protein and amyloid peptides, the main components of the neuropathological lesions of Alzheimer’s disease.

Rheumatoid arthritis

Rheumatoid arthritis is a chronic inflammatory disease that affects the joints. The disease occurs in outbreaks until the joints are destroyed. Several epidemiological studies have found an association between this disease and chronic periodontitis.

According to a 2020 study, “inflammation caused by periodontitis stimulates the production of cells that increase bone resorption in joints,” reports the Prevention Observatory of the Montreal Heart Institute.

Cancer

A 2016 study published in the journal Annals of Oncology points to a link between poor oral hygiene and head and neck cancer. “Good oral hygiene is associated with a lower risk of head and neck cancer,” the authors concluded.

Additionally, the Prevention Observatory reports several studies of this possible connection. A recent study (2022) concluded that the incidence of colorectal cancer is 50% higher in individuals with a history of periodontitis.

Additionally, periodontal bacteria have been observed in colorectal and oral cancers. And high levels of antibodies against P. gingivalis are associated with pancreatic cancer.

Risks during pregnancy

Finally, if it is difficult to establish a cause-and-effect relationship, periodontitis may have harmful consequences for pregnant women.

According to a medical dissertation defended in 2022, which reviewed the literature on the subject, “the presence of Porphyromonas gingivalis may cause a decrease in birth weight, but also an increase in the inflammatory response, which can lead to premature eclampsia and, as a result, premature birth .

Hi, I’m laayouni2023