” Whoever does it last will do well ” may have been Arthur Talman’s credo. An IRD biologist from the Mivegec laboratory has just received a grant from the European Research Council (ERC) for his research project on malaria. Called “Trojan” (English for “Trojan Horse”), it is designed to interfere with the interaction of the pathogen responsible for the disease with the host’s immune system.
” Malaria remains the leading cause of preventable death worldwide, with at least 631 deaths in 2023 000 deaths, according to the World Health Organization report. “,” the researcher recalls.
Despite the availability of a number of control tools, such as curative and preventive treatments, vaccines, insecticide-treated mosquito nets, and despite progress made since the early 2000s, the prospect of reducing the impact of malaria and eradicating it in the long term requires sustained investment. as well as the development of innovative control tools based on a better understanding of the biology of the parasite responsible for this disease, Plasmodium falciparum.
A game of hide and seek between the parasite and the immune system
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