survivors are at greater risk of developing other cancers

Breast cancer survivors: increased risk of endometrial and ovarian cancer

In their work, published April 24, the researchers focused on the risk of distant recurrence in breast cancer survivors, based on data from almost 600,000 patients in England.

The results of their analysis were published in the journalRegional Health Lancetshow that breast cancer survivors are at significantly higher risk of developing second cancers, including endometrial and ovarian cancer in women and prostate cancer in men.

In detail, breast cancer survivors had double the risk of developing contralateral breast cancer (in the other breast not affected by the first cancer) compared to the general population, andrisk of endometrial cancer increases by 87%58% myeloid leukemia and 25% ovarian cancer.

Breast cancer recurrence: possible influence of socioeconomic level

The team of researchers learned these lessons by analyzing data from the National Cancer Registry Dataset of 580,000 women and more than 3,500 men survivors of breast cancer diagnosed between 1995 and 2019.

This British study is the first to find a higher risk among people living in areas of great socioeconomic instability: women from disadvantaged backgrounds were 35% more likely to develop a second cancer compared to women from wealthier families.

L’Life style Researchers suspect that this may be the reason for this difference observed between socioeconomic conditions. They consider evidence that smoking, obesity and alcohol consumption are among the risk factors that may play a role in the development of other types of cancer (lung, kidney, bladder, stomach, etc.) and which are more common in the most disadvantaged groups population.

Recurrent Cancer: Are Young Breast Cancer Survivors at Greater Risk?

Age of diagnosis also acts as a criterion that may influence the risk of relapse, the researchers also noted.

Not in vain, Women diagnosed with breast cancer before age 50 the chance of developing a second primary cancer was 86% higher than the general population of the same age, while women diagnosed after age 50 had a 17% increased risk.

How can we explain this possible correlation between age and risk of relapse? Researchers suggest thatmore young breast cancer survivors [puissent avoir] inherited from genetic changes which increase the risk of multiple cancers. “For example, women who inherit changes in the BRCA1 and BRCA2 genes have an increased risk of developing contralateral breast cancer, ovarian cancer, and pancreatic cancer,” the researchers explain.

“It’s important for us to understand the extent to which having one type of cancer puts you at risk of having a second cancer elsewhere,” said Isaac Allen from the Department of Public Health and Primary School Care. at the University of Cambridge, lead author of the study.

The women and men breast cancer survivors we studied had an increased risk of developing a number of secondary cancers. This knowledge can help guide conversations with health care providers to identify signs of potential new cancers.”

To facilitate early detection of recurrence, women who have already had breast cancer are encouraged to have blood tests every 6 months and get a mammogram every yearexplained Dr. Alessandro Viansone, an oncologist, in a recent article in Medisite.