new treatment shows promising results against glioblastoma

If the creation of vaccination is already an unprecedented medical achievement, we continue to make other incredible advances in this field. The latest development in this field is, in particular, a vaccine against a very aggressive form of brain cancer. This vaccine has shown very promising results in clinical trials.

What is glioblastoma?

Glioblastoma multiforme is one of the most common forms of brain cancer. This malignant tumor, which affects the brain or spinal cord, is also one of the most malignant forms of brain cancer. Overall, the average survival time after diagnosis of glioblastoma multiforme is 16 months. Although treatments such as surgery, radiation therapy and chemotherapy remain possible for patients suffering from this type of cancer, glioblastoma multiforme is almost impossible to cure.

In other words, the best method to combat this disease is prevention. If we mainly promote a healthy lifestyle to prevent most diseases, this method has its limitations. Fortunately, there are medical means to prevent the disease, including vaccines. However, vaccines for various forms of cancer are still in their infancy. Despite this, we are beginning to make significant progress in this area. Recently, researchers from the University of Florida announced that they have successfully completed the first stages of clinical trials of a vaccine against glioblastoma multiforme.

Hope for patients

Indeed, according to a study published in the journal cellDuring a phase 1 clinical trial, the mRNA vaccine reprogrammed the immune systems of four patients in the study. This allowed their brain tumors to be attacked and, as a result, their survival rate increased by 50%. More importantly, the effect of the vaccine could be observed very quickly. Within just a few hours, the researchers noticed an increase in pro-inflammatory proteins, which are known to boost the immune system.

Although some side effects were also observed, including nausea, fever and chills, these quickly resolved. ” This was very surprising considering how quickly it happened; and what this told us was that we were able to very quickly activate the early part of the immune system against these cancers, which is key to unlocking the later effects of the immune response. “, explained Elias Sayour, lead author of the study. Note that previous clinical trials conducted on dogs showed equally promising results.

Moreover, you should know that this new experimental vaccine is personalized for each patient since it is produced using the latter’s tumor cells. The researchers also explained that the product’s delivery mechanism is very special and complex. ” Instead of introducing individual particles, we introduce groups of particles that wrap around each other like an onion, like a bag full of onions. “, explained Elias Sayur.

Plus, here are 10 bad things in your daily life that science has strongly linked to cancer.