Researchers are exploring the link between vitamin D and cancer resistance through the gut microbiota. The results in mice could be translated to humans if further research confirms them.
A diet rich in vitamin D affects the composition of the gut microbiota in mice, according to a new study published in the journal. The science. More precisely, this vitamin is synthesized by the skin when exposed to Sun or obtained through food – acts on the epithelial cells of the intestines, which increases the number of bacteria called Bacteroid fragile. Researchers write that this microbe let in the end mice resist tumor growth better (tumors transplanted into animals grow less) and respond more effectively to cancer immunotherapy. Thus, the results present vitamin D as a potential determinantimmunity against cancer and the success of immunotherapy, but researchers don’t yet know how.
The influence of microbiota on the human immune system
Previous studies have suggested a link between vitamin D levels and cancer risk in people, but without conclusive evidence. Although Bacteroid fragile is also present in the human microbiota, further research is needed to understand whether vitamin D also contributes to some resistance immune to cancer in humans.
” The key question we are now trying to answer is how vitamin D contributes to the formation of a “good” microbiota.said Evangelos Giampazolias, first author of the study and leader of the Cancer Immunosurveillance Group at Cancer Research UK Institute, Manchester Institute. If we can answer this question, we may be able to discover new ways in which the microbiota influences the immune system, which could open up exciting opportunities for prevention or cancer treatment. »
Related Posts
Aline Perrodin: the effects of cannabis on health – RTL
La politique sanitaire favoriserait la flambée des césariennes en Afrique
